Cheap flights to South Carolina from Detroit

Round trips from Detroit from $270. Cheapest dates, deal ratings and where to book.

• Columbia: $270, 2026-10-14 to 2026-10-18
• Charleston: $417, 2026-10-23 to 2026-10-26

Nearby

• North Carolina
• Georgia
• Virginia
• West Virginia
• Tennessee
• Alabama
• Kentucky
• Florida