Cheap flights to South Carolina from Chicago

Round trips from Chicago from $241. Cheapest dates, deal ratings and where to book.

• Charleston: $241, 2026-10-19 to 2026-10-21
• Myrtle Beach: $250, 2026-12-01 to 2026-12-03
• Columbia: $420, 2026-10-09 to 2026-10-18
• Greenville/Greer/Spartanburg: $649, 2026-10-09 to 2026-10-11

Nearby

• North Carolina
• Georgia
• Virginia
• West Virginia
• Tennessee
• Alabama
• Kentucky
• Florida