Cheap flights to South Carolina from Chicago

Round trips from Chicago from $230. Cheapest dates, deal ratings and where to book.

• Columbia: $230, 2026-10-09 to 2026-10-18
• Myrtle Beach: $263, 2026-12-01 to 2026-12-03
• Charleston: $270, 2026-10-19 to 2026-10-21
• Greenville/Greer/Spartanburg: $466, 2026-10-09 to 2026-10-11

Nearby

• North Carolina
• Georgia
• Virginia
• West Virginia
• Tennessee
• Alabama
• Kentucky
• Florida